[Ip-health] Why Are These Fraudulent Papers Unretracted?

Riaz K Tayob riaz.tayob at gmail.com
Tue May 1 01:37:54 PDT 2012

[So much for evidence based health... and peer review...]

Big Pharma's Ghostwriters

  Why Are These Fraudulent Papers Unretracted?


According to Science Times[1], 
the Tuesday science section in the /New York Times/, scientific 
retractions are on the rise because of a "dysfunctional scientific 
climate" that has created a "winner-take-all game with perverse 
incentives that lead scientists to cut corners and, in some cases, 
commit acts of misconduct."

But elsewhere, audacious, falsified research stands 
unretracted--including the work of authors who actually went to prison 
for fraud!

Richard Borison, MD, former psychiatry chief at the Augusta Veterans 
Affairs medical center and Medical College of Georgia, was sentenced to 
15 years in prison for a $10 million clinical trial fraud[2] 
but his 1996 US Seroquel® Study Group research is unretracted.[3] 
In fact, it is cited in 173 works and medical textbooks, misleading 
future medical professionals.[4] 

Scott Reuben, MD, the "Bernie Madoff" of medicine who published research 
on clinical trials that never existed, was sentenced to six months in 
prison in 2010.[5] 
But his "research" on popular pain killers like Celebrex and Lyrica is 
If going to prison for research fraud is not enough reason for 
retraction, what is?

Wayne MacFadden, MD, resigned as US medical director for Seroquel in 
2006, after sexual affairs with two coworker women researchers 
but the related work is unretracted and was even part of Seroquel's FDA 
approval package for bipolar disorder.[8] 

More than 50 ghostwritten papers about hormone therapy (HT) written by 
Pfizer's marketing firm, Designwrite, ran in medical journals, according 
to unsealed court documents on the University of California--San 
Francisco's Drug Industry Document Archive.[9] 
Though the papers claimed no link between HT and breast cancer and false 
cardiac and cognitive benefits and were ghostwritten by /marketing 
professionals not doctors,/ none has been retracted.

Pfizer/Parke-Davis placed 13 ghostwritten articles[10] 
in medical journals promoting Neurontin for offlabel uses, including a 
supplement to the /Cleveland Clinic/[11] 
but only Cochrane Database Systematic Reviews and Protocols has 
retracted the specious articles.[12] 

Nor is the phony science just a product of "Big Pharma." In 2008, JAMA 
was forced to print a correction stating that authors of an article 
arguing for a higher recommended dietary allowance of protein were, in 
fact, industry operatives. [13] 
Sharon L. Miller was "formerly employed by the National Cattlemen's Beef 
Association," and author Robert R. Wolfe, PhD, received money from the 
Egg Nutrition Center, the National Dairy Council, the National Pork 
Board, and the Beef Checkoff through the National Cattlemen's Beef 
Association, said the clarification. Miller's email address, in fact was 
smiller at beef.org, which should might have been the JAMA editors' first 
The article has also not been retracted.

/*Martha Rosenberg's* is an investigative health reporter. Her first 
book, Born With A Junk Food Deficiency: How Flaks, Quacks and Hacks Pimp 
The Public Health 
<http://www.amazon.com/exec/obidos/ASIN/1616145935/counterpunchmaga>, has just 
been released by Prometheus books./



Steve Stecklow and Laura Johannes, "Test Case: Drug Makers Relied on Two 
Researchers Who Now Await Trial," Wall Street Journal, August 8, 1997

Richard Borison et al., "ICI 204,636, an Atypical Antipsychotic: 
Efficacy and Safety in a Multicenter, Placebo-Controlled Trial in 
Patients with Schizophrenia," Journal of Clinical Psychopharmacology 16, 
no. 2 (April 1996): 158--69

Alan F. Schatzberg and Charles B. Nemeroff, Textbook of 
Psychopharmacology (New York: American Psychiatric Publishing, 2009) p. 609


Scott Reuben et al., "The Analgesic Efficacy of Celecoxib, Pregabalin, 
and Their Combination for Spinal Fusion Surgery," Anesthesia & Analgesia 
103, no. 5 (November 2006): 1271--77.


http://www.lifesciencesworld.com/news/view/12152 (BOLDER study)

Martha Rosenberg, "Flash Back. The Troubling Revival of Hormone Therapy. 
Consumers Digest, November 2010

Kristina Fiore, "Journals Aided in Marketing of Gabapentin," MedPage 
Today, September 11, 2009

United States District Court, District of Massachusetts, Report on the 
Use of Neurontin for Bipolar and Other Mood 

P. J. Wiffen et al., "WITHDRAWN: Gabapentin for Acute and Chronic Pain," 
Cochrane Database Systematic Reviews and Protocols 16, no. 3 (March 16, 
2011); P. J. Wiffen et al., "WITHDRAWN: Anticonvulsant Drugs for Acute 
and Chronic Pain," Cochrane Database Systematic Reviews and Protocols 
no. 1 (January 20, 2010);



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