[Ip-health] PAHO: Countries of the Americas choose innovative projects for the development of drugs and technologies

Thiru Balasubramaniam thiru at keionline.org
Tue Oct 29 06:09:36 PDT 2013


Countries of the Americas choose innovative projects for the development of
drugs and technologies<http://www.paho.org/hq/index.php?option=com_content&view=article&id=9113%3Acountries-of-the-americas-choose-innovative-projects-for-the-development-of-drugs-and-technologies-&catid=1443%3Anews-front-page-items&Itemid=1926&lang=en>

*Initiatives selected by consensus will represent the region at the World
Health Organization*

*Washington, D.C., 28 October 2013 (PAHO/WHO) – *This October
of health authorities from 19 countries in the Americas selected, by
consensus, four innovative projects for research and development of
medicines and other health technologies. The projects will represent the
region before the Committee of World Experts that meets in December in the
World Health Organization (WHO).

The chosen proposals include generating a coordination mechanism for the
development of new tools for Chagas disease, the development of a vaccine
against schistosomiasis, a diagnostic test for fever or sepsis and a novel
treatment for cutaneous leishmaniasis. Three other projects were selected
as alternatives and have to do with developing affordable tests for cancer
diagnosis, a mechanism for accelerating access to medicines for
tuberculosis and a diagnostic kit for prenatal and postpartum diseases.

Representatives of the ministries of health of 19 countries of the Americas
gathered on 22 and 23 October at the Pan American Health Organization
(PAHO) headquarters and selected these proposals according to their
technical feasibility and scientific bases.

Additionally, they assessed the projects on the basis of their proposed
innovative financing and coordination mechanisms, which was expected to be
framed within the recommendations of the Consultative Group of experts
Group report on research and development: funding and coordination (CEWG),
which urges countries to establish new mechanisms (and strengthen existing
ones) to improve the research and development of health technologies to
address the gaps in public health in low-income countries.

The delegates considered that the projects should take into account the
importance of improving access to health technologies in developing
countries and use mechanisms that allow the delinking of the cost of
research and development and the price at which the product is marketed.

This selection process is part of a global initiative that involves the six
WHO regions and that will culminate in the selection of a limited number of
"demonstration projects" to be presented during the World Health Assembly
in 2014.

There were 29 submissions for the region of the Americas. The call for
proposals was open to all sectors, including representatives of civil
society, the academic centers and research, the private sector and
nongovernmental organizations of public health. PAHO/WHO coordinated the
process and the appeal, insofar as the Member States had the responsibility
for selecting projects that will represent the region of the Americas
according to very specific criteria.

In May of 2013, the 66th World Health Assembly adopted a resolution that
urges  WHO and its regional offices and Member States to identify gaps in
research and development related to the development, manufacturing and
distribution of products. It also establishes the need to identify projects
that demonstrate innovative mechanisms of financing and coordination for
research and development of medicines, diagnostic or other health
technologies, with the ultimate goal of increasing access to these for the
most vulnerable populations.

*Selected projects (no order of priority):*

1.  Chagas R & D Accelerator Initiative: a coordination mechanism for
accelerating the development of new health tools for Chagas diseases

2.  Development of a vaccine against schistosomiasis based on the
recombinant SM14 a member of the fatty acid binding protein: controlling
transmission of a disease of poverty

3.  Ecosystem for Financing Development of an Open Source Multiplex Point
of Care (POC) Diagnostic Test for the Differential Diagnosis of Fever or
Sepsis, Henceforward, this will be referred to as the Open Source Fever
Diagnostic Project)

4.  Development of a Class D CPG ODN (D35 as an adjunct to chemotherapy for
cutaneous leishmaniasis and post Kala-Azar Dermal Leishmaniasis (PKDL)

*Alternative projects (in order of priority)*

5. Affordable Diagnostic Tests for Cancer

6. Accelerating Innovation and Access to Medicines for Tuberculosis Through
Open Collaboration: A Push, Pull, Pool Approach ("The 3 p Project”)

7. Establishment of Public-Private Partnership for the Development of a
Diagnostic Kit for Prenatal and Postpartum)

Table of selection of projects

*Related links*

   - WHO.WHA66.22 point 17.2 of the order of the day. Follow-up to the
   report of the Consultative Group of experts on research and development:
   funding and coordination<http://www.wpro.who.int/health_research/WHA66.22_CEWG.pdf>

   - Regional Platform on access and innovation for health technologies
   - WHO web page on intellectual

Last Updated on Monday, 28 October 2013 13:41

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